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Cleavage of the selective autophagy receptor SQSTM1/p62 by the SARS-CoV-2 main protease NSP5 prevents the autophagic degradation of viral membrane proteins

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) global pandemic. Omicron, a new variant of SARS-CoV-2, has the characteristics of strong transmission and pathogenicity, short incubation period, and rapid onset progression, and has sprea...

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Detalles Bibliográficos
Autores principales: Zhang, Yabin, Liu, Shiyan, Xu, Qingjia, Li, Huihui, Lu, Kefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162485/
https://www.ncbi.nlm.nih.gov/pubmed/35654983
http://dx.doi.org/10.1186/s43556-022-00083-2