Bone Mesenchymal Stem Cell-Derived Exosome-Enclosed miR-181a Induces CD4(+)CD25(+)FOXP3(+) Regulatory T Cells via SIRT1/Acetylation-Mediated FOXP3 Stabilization

Bone marrow mesenchymal stem cells (BMSCs) have been identified as a potential therapeutic approach to immune-related diseases. Here, we show that BMSC-derived exosomes promote FOXP3 expression and induce the conversion of CD4(+) T cells into CD4(+)CD25(+)FOXP3(+) Treg cells, which is significant fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Renyong, Li, Ruixue, Li, Tiehan, Zhu, Lei, Qi, Zongze, Yang, Xiaokui, Wang, Huan, Cao, Baoquan, Zhu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162841/
https://www.ncbi.nlm.nih.gov/pubmed/35664563
http://dx.doi.org/10.1155/2022/8890434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162841/
https://www.ncbi.nlm.nih.gov/pubmed/35664563
http://dx.doi.org/10.1155/2022/8890434

Ejemplares similares