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Bone Mesenchymal Stem Cell-Derived Exosome-Enclosed miR-181a Induces CD4(+)CD25(+)FOXP3(+) Regulatory T Cells via SIRT1/Acetylation-Mediated FOXP3 Stabilization

Bone marrow mesenchymal stem cells (BMSCs) have been identified as a potential therapeutic approach to immune-related diseases. Here, we show that BMSC-derived exosomes promote FOXP3 expression and induce the conversion of CD4(+) T cells into CD4(+)CD25(+)FOXP3(+) Treg cells, which is significant fo...

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Detalles Bibliográficos
Autores principales:	Wang, Renyong, Li, Ruixue, Li, Tiehan, Zhu, Lei, Qi, Zongze, Yang, Xiaokui, Wang, Huan, Cao, Baoquan, Zhu, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162841/ https://www.ncbi.nlm.nih.gov/pubmed/35664563 http://dx.doi.org/10.1155/2022/8890434

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