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Identification of a c-MYB-directed therapeutic for acute myeloid leukemia

A significant proportion of patients suffering from acute myeloid leukemia (AML) cannot be cured by conventional chemotherapy, relapsed disease being a common problem. Molecular targeting of essential oncogenic mediators is an attractive approach to improving outcomes for this disease. The hematopoi...

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Detalles Bibliográficos
Autores principales: Clesham, Katherine, Walf-Vorderwülbecke, Vanessa, Gasparoli, Luca, Virely, Clemence, Cantilena, Sandra, Tsakaneli, Alexia, Inglott, Sarah, Adams, Stuart, Samarasinghe, Sujith, Bartram, Jack, Williams, Gareth, de Boer, Jasper, Williams, Owen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162920/
https://www.ncbi.nlm.nih.gov/pubmed/35368048
http://dx.doi.org/10.1038/s41375-022-01554-9