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Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma

Peripheral T-cell lymphoma (PTCL) is a rare, heterogenous malignancy with dismal outcomes at relapse. Hypomethylating agents (HMA) have an emerging role in PTCL, supported by shared mutations with myelodysplasia (MDS). Response rates to azacitidine in PTCL of follicular helper cell origin are promis...

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Detalles Bibliográficos
Autores principales: Wong, Jonathan, Gruber, Emily, Maher, Belinda, Waltham, Mark, Sabouri-Thompson, Zahra, Jong, Ian, Luong, Quinton, Levy, Sidney, Kumar, Beena, Brasacchio, Daniella, Jia, Wendy, So, Joan, Skinner, Hugh, Lewis, Alexander, Hogg, Simon J., Vervoort, Stephin, DiCorleto, Carmen, Uhe, Micheleine, Gamgee, Jeanette, Opat, Stephen, Gregory, Gareth P., Polekhina, Galina, Reynolds, John, Hawkes, Eliza A., Kailainathan, Gajan, Gasiorowski, Robin, Kats, Lev M., Shortt, Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162925/
https://www.ncbi.nlm.nih.gov/pubmed/35459873
http://dx.doi.org/10.1038/s41375-022-01571-8