A single allele of the hsa-miR-302/367 cluster maintains human pluripotent stem cells

INTRODUCTION: In a diploid organism, two alleles from a single genetic locus are expressed to generate a normal phenotype. Heterozygous deleterious mutation causes a reduction of functional proteins to a half dose and insufficient amounts of functional proteins can occur to generate an in–normal phe...

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Detalles Bibliográficos
Autores principales: Sugawara, Tohru, Kawamoto, Yuki, Kawasaki, Tomoyuki, Umezawa, Akihiro, Akutsu, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162946/
https://www.ncbi.nlm.nih.gov/pubmed/35702483
http://dx.doi.org/10.1016/j.reth.2022.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162946/
https://www.ncbi.nlm.nih.gov/pubmed/35702483
http://dx.doi.org/10.1016/j.reth.2022.05.005

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