Development of an automated closed-loop β-blocker delivery system to stably reduce myocardial oxygen consumption without inducing circulatory collapse in a canine heart failure model: a proof of concept study

Beta-blockers are well known to reduce myocardial oxygen consumption (MVO(2)) and improve the prognosis of heart failure (HF) patients. However, its negative chronotropic and inotropic effects limit their use in the acute phase of HF due to the risk of circulatory collapse. In this study, as a first...

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Detalles Bibliográficos
Autores principales: Nishikawa, Takuya, Uemura, Kazunori, Hayama, Yohsuke, Kawada, Toru, Saku, Keita, Sugimachi, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162998/
https://www.ncbi.nlm.nih.gov/pubmed/33969457
http://dx.doi.org/10.1007/s10877-021-00717-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162998/
https://www.ncbi.nlm.nih.gov/pubmed/33969457
http://dx.doi.org/10.1007/s10877-021-00717-w

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