The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells

The first cell fate commitment during mammalian development is the specification of the inner cell mass and trophectoderm. This irreversible cell fate commitment should be epigenetically regulated, but the precise mechanism is largely unknown in humans. Here, we show that naïve human embryonic stem...

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Detalles Bibliográficos
Autores principales: Kobayashi, Norio, Okae, Hiroaki, Hiura, Hitoshi, Kubota, Naoto, Kobayashi, Eri H., Shibata, Shun, Oike, Akira, Hori, Takeshi, Kikutake, Chie, Hamada, Hirotaka, Kaji, Hirokazu, Suyama, Mikita, Bortolin-Cavaillé, Marie-Line, Cavaillé, Jérôme, Arima, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163035/
https://www.ncbi.nlm.nih.gov/pubmed/35654791
http://dx.doi.org/10.1038/s41467-022-30775-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163035/
https://www.ncbi.nlm.nih.gov/pubmed/35654791
http://dx.doi.org/10.1038/s41467-022-30775-w

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