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Discovery of the cyclotide caripe 11 as a ligand of the cholecystokinin-2 receptor
The cholecystokinin-2 receptor (CCK(2)R) is a G protein-coupled receptor (GPCR) that is expressed in peripheral tissues and the central nervous system and constitutes a promising target for drug development in several diseases, such as gastrointestinal cancer. The search for ligands of this receptor...
Autores principales: | Taghizadeh, Mohammad Sadegh, Retzl, Bernhard, Muratspahić, Edin, Trenk, Christoph, Casanova, Emilio, Moghadam, Ali, Afsharifar, Alireza, Niazi, Ali, Gruber, Christian W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163038/ https://www.ncbi.nlm.nih.gov/pubmed/35654807 http://dx.doi.org/10.1038/s41598-022-13142-z |
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