HER2 G776S mutation promotes oncogenic potential in colorectal cancer cells when accompanied by loss of APC function

Clinical cancer genome sequencing detects oncogenic variants that are potential targets for cancer treatment, but it also detects variants of unknown significance. These variants may interact with each other to influence tumor pathophysiology, however, such interactions have not been fully elucidate...

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Detalles Bibliográficos
Autores principales: Mitani, Yosuke, Ohashi, Shinya, Kikuchi, Osamu, Nakai, Yukie, Ida, Tomomi, Mizumoto, Ayaka, Yamamoto, Yoshihiro, Saito, Tomoki, Kataoka, Shigeki, Matsubara, Junichi, Yamada, Atsushi, Kanai, Masashi, Matsumoto, Shigemi, Sakai, Hiroaki, Yoshikawa, Kiyotsugu, Nakamura, Eijiro, Muto, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163061/
https://www.ncbi.nlm.nih.gov/pubmed/35654814
http://dx.doi.org/10.1038/s41598-022-13189-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163061/
https://www.ncbi.nlm.nih.gov/pubmed/35654814
http://dx.doi.org/10.1038/s41598-022-13189-y

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