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Direct interaction of a chaperone-bound type III secretion substrate with the export gate

Several gram-negative bacteria employ type III secretion systems (T3SS) to inject effector proteins into eukaryotic host cells directly from the bacterial cytoplasm. The export gate SctV (YscV in Yersinia) binds substrate:chaperone complexes such as YscX:YscY, which are essential for formation of a...

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Detalles Bibliográficos
Autores principales: Gilzer, Dominic, Schreiner, Madeleine, Niemann, Hartmut H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163089/
https://www.ncbi.nlm.nih.gov/pubmed/35654781
http://dx.doi.org/10.1038/s41467-022-30487-1