Cargando…

Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers

Hypoxia, a driver of tumor growth and metastasis, regulates angiogenic pathways that are targets for vessel normalization and ovarian cancer management. However, toxicities and resistance to anti-angiogenics can limit their use making identification of new targets vital. Inhibin, a heteromeric TGFβ...

Descripción completa

Detalles Bibliográficos
Autores principales: Horst, Ben, Pradhan, Shrikant, Chaudhary, Roohi, Listik, Eduardo, Quintero-Macias, Liz, Choi, Alex Seok, Southard, Michael, Liu, Yingmiao, Whitaker, Regina, Hempel, Nadine, Berchuck, Andrew, Nixon, Andrew B., Lee, Nam Y., Henis, Yoav I., Mythreye, Karthikeyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163327/
https://www.ncbi.nlm.nih.gov/pubmed/35654828
http://dx.doi.org/10.1038/s42003-022-03495-6