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RAISING is a high-performance method for identifying random transgene integration sites

Both natural viral infections and therapeutic interventions using viral vectors pose significant risks of malignant transformation. Monitoring for clonal expansion of infected cells is important for detecting cancer. Here we developed a novel method of tracking clonality via the detection of transge...

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Detalles Bibliográficos
Autores principales: Wada, Yusaku, Sato, Tomoo, Hasegawa, Hiroo, Matsudaira, Takahiro, Nao, Naganori, Coler-Reilly, Ariella L. G., Tasaka, Tomohiko, Yamauchi, Shunsuke, Okagawa, Tomohiro, Momose, Haruka, Tanio, Michikazu, Kuramitsu, Madoka, Sasaki, Daisuke, Matsumoto, Nariyoshi, Yagishita, Naoko, Yamauchi, Junji, Araya, Natsumi, Tanabe, Kenichiro, Yamagishi, Makoto, Nakashima, Makoto, Nakahata, Shingo, Iha, Hidekatsu, Ogata, Masao, Muramatsu, Masamichi, Imaizumi, Yoshitaka, Uchimaru, Kaoru, Miyazaki, Yasushi, Konnai, Satoru, Yanagihara, Katsunori, Morishita, Kazuhiro, Watanabe, Toshiki, Yamano, Yoshihisa, Saito, Masumichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163355/
https://www.ncbi.nlm.nih.gov/pubmed/35654946
http://dx.doi.org/10.1038/s42003-022-03467-w