Human Melanoma-Associated Mast Cells Display a Distinct Transcriptional Signature Characterized by an Upregulation of the Complement Component 3 That Correlates With Poor Prognosis

Cutaneous melanoma is one of the most aggressive human malignancies and shows increasing incidence. Mast cells (MCs), long-lived tissue-resident cells that are particularly abundant in human skin where they regulate both innate and adaptive immunity, are associated with melanoma stroma (MAMCs). Thus...

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Detalles Bibliográficos
Autores principales: Bahri, Rajia, Kiss, Orsolya, Prise, Ian, Garcia-Rodriguez, Karen M., Atmoko, Haris, Martínez-Gómez, Julia M., Levesque, Mitchell P., Dummer, Reinhard, Smith, Michael P., Wellbrock, Claudia, Bulfone-Paus, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163391/
https://www.ncbi.nlm.nih.gov/pubmed/35669782
http://dx.doi.org/10.3389/fimmu.2022.861545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163391/
https://www.ncbi.nlm.nih.gov/pubmed/35669782
http://dx.doi.org/10.3389/fimmu.2022.861545

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