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The Metabolic and Non-Metabolic Roles of UCK2 in Tumor Progression

Enhanced nucleoside metabolism is one of the hallmarks of cancer. Uridine-cytidine kinase 2 (UCK2) is a rate-limiting enzyme of the pyrimidine salvage synthesis pathway to phosphorylate uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. Recent studies...

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Detalles Bibliográficos
Autores principales: Fu, Yi, Wei, Xin-dong, Guo, Luoting, Wu, Kai, Le, Jiamei, Ma, Yujie, Kong, Xiaoni, Tong, Ying, Wu, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163393/
https://www.ncbi.nlm.nih.gov/pubmed/35669416
http://dx.doi.org/10.3389/fonc.2022.904887