Antisense transcription from lentiviral gene targeting linked to an integrated stress response in colorectal cancer cells

Advances in gene therapy research have resulted in the successful development of new therapies for clinical use. Here, we explored a gene targeting approach to deplete ephrinB2 from colorectal cancer cells using an inducible lentiviral vector. EphrinB2, a transmembrane ephrin ligand, promotes colore...

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Detalles Bibliográficos
Autores principales: Ha, Taekyu, DiPrima, Michael, Koparde, Vishal, Jailwala, Parthav, Ohnuki, Hidetaka, Feng, Jing-Xin, Palangat, Murali, Larson, Daniel, Tosato, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163427/
https://www.ncbi.nlm.nih.gov/pubmed/35694213
http://dx.doi.org/10.1016/j.omtn.2022.05.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163427/
https://www.ncbi.nlm.nih.gov/pubmed/35694213
http://dx.doi.org/10.1016/j.omtn.2022.05.029

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