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Antisense transcription from lentiviral gene targeting linked to an integrated stress response in colorectal cancer cells
Advances in gene therapy research have resulted in the successful development of new therapies for clinical use. Here, we explored a gene targeting approach to deplete ephrinB2 from colorectal cancer cells using an inducible lentiviral vector. EphrinB2, a transmembrane ephrin ligand, promotes colore...
Autores principales: | Ha, Taekyu, DiPrima, Michael, Koparde, Vishal, Jailwala, Parthav, Ohnuki, Hidetaka, Feng, Jing-Xin, Palangat, Murali, Larson, Daniel, Tosato, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163427/ https://www.ncbi.nlm.nih.gov/pubmed/35694213 http://dx.doi.org/10.1016/j.omtn.2022.05.029 |
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