ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1

Diabetic cardiomyopathy (DCM) is a major complication of diabetes, but its underlying mechanisms still remain unclear. The multifunctional protein Y-box binding protein-1 (YB-1) plays an important role in cardiac pathogenesis by regulating cardiac apoptosis, cardiac fibrosis, and pathological remode...

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Detalles Bibliográficos
Autores principales: Zhong, Xiaodan, Wang, Tao, Zhang, Wenjun, Wang, Mengwen, Xie, Yang, Dai, Lei, He, Xingwei, Madhusudhan, Thati, Zeng, Hesong, Wang, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163515/
https://www.ncbi.nlm.nih.gov/pubmed/35490780
http://dx.doi.org/10.1016/j.jbc.2022.101989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163515/
https://www.ncbi.nlm.nih.gov/pubmed/35490780
http://dx.doi.org/10.1016/j.jbc.2022.101989

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