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Chronic Obstructive Pulmonary Disease Is Associated with Epigenome-Wide Differential Methylation in BAL Lung Cells

DNA methylation patterns in chronic pulmonary obstructive disease (COPD) might offer new insights into disease pathogenesis. To assess methylation profiles in the main COPD target organ, we performed an epigenome-wide association study on BAL cells. Bronchoscopies were performed in 18 subjects with...

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Detalles Bibliográficos
Autores principales: Eriksson Ström, Jonas, Kebede Merid, Simon, Pourazar, Jamshid, Blomberg, Anders, Lindberg, Anne, Ringh, Mikael V., Hagemann-Jensen, Michael, Ekström, Tomas J., Behndig, Annelie F., Melén, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163645/
https://www.ncbi.nlm.nih.gov/pubmed/35286818
http://dx.doi.org/10.1165/rcmb.2021-0403OC