ERK-Smurf1-RhoA signaling is critical for TGFβ-drived EMT and tumor metastasis

Epithelial-mesenchymal transition (EMT) has fundamental roles in various biological processes. However, there are still questions pending in this fast-moving field. Here we report that in TGFβ-induced EMT, ERK-mediated Smurf1 phosphorylation is a prerequisite step for RhoA degradation and the conseq...

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Detalles Bibliográficos
Autores principales: Zheng, Jianzhong, Shi, Zhiyuan, Yang, Pengbo, Zhao, Yue, Tang, Wenbin, Ye, Shaopei, Xuan, Zuodong, Chen, Chen, Shao, Chen, Wu, Qingang, Sun, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163791/
https://www.ncbi.nlm.nih.gov/pubmed/35654587
http://dx.doi.org/10.26508/lsa.202101330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163791/
https://www.ncbi.nlm.nih.gov/pubmed/35654587
http://dx.doi.org/10.26508/lsa.202101330

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