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Pharmacokinetics and Pharmacodynamics of Colistin Combined With Isopropoxy Benzene Guanidine Against mcr-1-Positive Salmonella in an Intestinal Infection Model

Plasmid-borne colistin resistance mediated by mcr-1 is a growing problem, which poses a serious challenge to the clinical application of colistin for Gram-negative bacterial infections. Drug combination is one of the effective strategies to treat colistin-resistant bacteria. Here, we found a guanidi...

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Detalles Bibliográficos
Autores principales: Kong, Lingli, Lu, Yixing, Yang, Liuye, Zhang, Wanying, Zuo, Beini, Peng, Xianfeng, Qin, Zonghua, Li, Miao, Zeng, Zhenling, Zeng, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163831/
https://www.ncbi.nlm.nih.gov/pubmed/35668766
http://dx.doi.org/10.3389/fmicb.2022.907116