Bindarit Reduces Bone Loss in Ovariectomized Mice by Inhibiting CCL2 and CCL7 Expression via the NF‐κB Signaling Pathway

OBJECTIVE: To investigate the changes in proinflammatory cytokines and chemokines, namely, C‐C motif ligand (CCL) 2 and CCL7, in postmenopausal osteoporosis (PMOP) and to develop a new drug, bindarit (Bnd), for PMOP in an ovariectomized (OVX) mouse model. METHODS: Bone marrow macrophages (BMMs) from...

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Detalles Bibliográficos
Autores principales: Yuan, Shi‐guo, Hu, Hong‐ling, Wang, Xin‐jia, Yang, Jin‐cheng, Zhou, Rong‐ping, Bai, Xiao‐chun, Lai, Ping‐lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163972/
https://www.ncbi.nlm.nih.gov/pubmed/35470579
http://dx.doi.org/10.1111/os.13252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163972/
https://www.ncbi.nlm.nih.gov/pubmed/35470579
http://dx.doi.org/10.1111/os.13252

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