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Beneficial Effect of Fenofibrate and Silymarin on Hepatic Steatosis and Gene Expression of Lipogenic and Cytochrome P450 Enzymes in Non-Obese Hereditary Hypertriglyceridemic Rats

The efficacy of fenofibrate in the treatment of hepatic steatosis has not been clearly demonstrated. In this study, we investigated the effects of fenofibrate and silymarin, administered as monotherapy and in combination to existing hepatic steatosis in a unique strain of hereditary hypertriglycerid...

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Detalles Bibliográficos
Autores principales: Vecera, Rostislav, Poruba, Martin, Hüttl, Martina, Malinska, Hana, Oliyarnyk, Olena, Markova, Irena, Racova, Zuzana, Soukop, Jan, Kazdova, Ludmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164080/
https://www.ncbi.nlm.nih.gov/pubmed/35678658
http://dx.doi.org/10.3390/cimb44050129