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High Fluoride Ingestion Impairs Bone Fracture Healing by Attenuating M2 Macrophage Differentiation

Fluorosis is still endemic in at least 25 countries around the world. In this study, we investigated the effect of high fluoride intake on fracture healing. Our in vitro experiments found that fluoride inhibited the osteogenic and angiogenic differentiation of MSCs in a dose-dependent manner. By con...

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Detalles Bibliográficos
Autores principales: Du, Chengcheng, Xiao, Pengcheng, Gao, Shengqiang, Chen, Shengwen, Chen, Bowen, Huang, Wei, Zhao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164140/
https://www.ncbi.nlm.nih.gov/pubmed/35669059
http://dx.doi.org/10.3389/fbioe.2022.791433