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Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology

BACKGROUND: Multiple system atrophy (MSA) is a rare, progressive, neurodegenerative disorder presenting glia pathology. Still, disease etiology and pathophysiology are unknown, but neuro-inflammation and vascular disruption may be contributing factors to the disease progression. Here, we performed a...

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Detalles Bibliográficos
Autores principales: Rydbirk, Rasmus, Østergaard, Ole, Folke, Jonas, Hempel, Casper, DellaValle, Brian, Andresen, Thomas L., Løkkegaard, Annemette, Hejl, Anne-Mette, Bode, Matthias, Blaabjerg, Morten, Møller, Mette, Danielsen, Erik H., Salvesen, Lisette, Starhof, Charlotte C., Bech, Sara, Winge, Kristian, Rungby, Jørgen, Pakkenberg, Bente, Brudek, Tomasz, Olsen, Jesper V., Aznar, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164190/
https://www.ncbi.nlm.nih.gov/pubmed/35657417
http://dx.doi.org/10.1007/s00018-022-04378-z