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Template-Assisted Crystallization Behavior in Stirred Solutions of the Monoclonal Antibody Anti-CD20: Probability Distributions of Induction Times

[Image: see text] We present a method to determine the template crystallization behavior of proteins. This method is a statistical approach that accounts for the stochastic nature of nucleation. It makes use of batch-wise experiments under stirring conditions in volumes smaller than 0.3 mL to save m...

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Detalles Bibliográficos
Autores principales: Gerard, Charline J. J., Briuglia, Maria L., Rajoub, Nazer, Mastropietro, Teresa F., Chen, Wenqian, Heng, Jerry Y. Y., Di Profio, Gianluca, ter Horst, Joop H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164231/
https://www.ncbi.nlm.nih.gov/pubmed/35673394
http://dx.doi.org/10.1021/acs.cgd.1c01324