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Expeditive Synthesis of Potent C20-epi-Amino Derivatives of Salinomycin against Cancer Stem-Like Cells

[Image: see text] As a continuation of our studies toward the development of small molecules to selectively target cancer stem cells (CSCs), a library of 18 novel derivatives of salinomycin (Sal), a naturally occurring polyether ionophore, was synthesized with a good overall yield using a one-pot Mi...

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Detalles Bibliográficos
Autores principales: Czerwonka, Dominika, Müller, Sebastian, Cañeque, Tatiana, Colombeau, Ludovic, Huczyński, Adam, Antoszczak, Michał, Rodriguez, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164233/
https://www.ncbi.nlm.nih.gov/pubmed/35673680
http://dx.doi.org/10.1021/acsorginorgau.1c00046