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Rapid Access to Ironomycin Derivatives by Click Chemistry

[Image: see text] Salinomycin, a natural carboxylic polyether ionophore, shows a very interesting spectrum of biological activities, including selective toxicity toward cancer stem cells (CSCs). Recently, we have developed a C20-propargylamine derivative of salinomycin (ironomycin) that exhibits mor...

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Detalles Bibliográficos
Autores principales: Antoszczak, Michał, Müller, Sebastian, Colombeau, Ludovic, Cañeque, Tatiana, Rodriguez, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164236/
https://www.ncbi.nlm.nih.gov/pubmed/35673682
http://dx.doi.org/10.1021/acsorginorgau.1c00045