The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal

The endogenous DNA damage triggering an aging progression in the elderly is prevented in the youth, probably by naturally occurring DNA gaps. Decreased DNA gaps are found during chronological aging in yeast. So we named the gaps “Youth‐DNA‐GAPs.” The gaps are hidden by histone deacetylation to preve...

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Detalles Bibliográficos
Autores principales: Yasom, Sakawdaurn, Watcharanurak, Papitchaya, Bhummaphan, Narumol, Thongsroy, Jirapan, Puttipanyalears, Charoenchai, Settayanon, Sirapat, Chalertpet, Kanwalat, Khumsri, Wilunplus, Kongkaew, Aphisek, Patchsung, Maturada, Siriwattanakankul, Chutha, Pongpanich, Monnat, Pin‐on, Piyapat, Jindatip, Depicha, Wanotayan, Rujira, Odton, Mingkwan, Supasai, Suangsuda, Oo, Thura Tun, Arunsak, Busarin, Pratchayasakul, Wasana, Chattipakorn, Nipon, Chattipakorn, Siriporn, Mutirangura, Apiwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164245/
https://www.ncbi.nlm.nih.gov/pubmed/35664831
http://dx.doi.org/10.1096/fba.2021-00131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164245/
https://www.ncbi.nlm.nih.gov/pubmed/35664831
http://dx.doi.org/10.1096/fba.2021-00131

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