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Malondialdehyde Acetaldehyde-Adduction Changes Surfactant Protein D Structure and Function

Alcohol consumption with concurrent cigarette smoking produces malondialdehyde acetaldehyde (MAA)-adducted lung proteins. Lung surfactant protein D (SPD) supports innate immunity via bacterial aggregation and lysis, as well as by enhancing macrophage-binding and phagocytosis. MAA-adducted SPD (SPD-M...

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Detalles Bibliográficos
Autores principales: Nissen, Claire G., Mosley, Deanna D., Kharbanda, Kusum K., Katafiasz, Dawn M., Bailey, Kristina L., Wyatt, Todd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164268/
https://www.ncbi.nlm.nih.gov/pubmed/35669781
http://dx.doi.org/10.3389/fimmu.2022.866795