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Cyclosporine A loaded brain targeting nanoparticle to treat cerebral ischemia/reperfusion injury in mice

BACKGROUND: Ischemic stroke is one of the main causes of death and disability in the world. The treatment for ischemic stroke is to restore blood perfusion as soon as possible. However, when ischemic brain tissue is re-perfused by blood, the mitochondrial permeability transition pore (mPTP) in neuro...

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Detalles Bibliográficos
Autores principales: Liu, Daozhou, Ji, Qifeng, Cheng, Ying, Liu, Miao, Zhang, Bangle, Mei, Qibing, Huan, Menglei, Zhou, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164331/
https://www.ncbi.nlm.nih.gov/pubmed/35658867
http://dx.doi.org/10.1186/s12951-022-01474-x