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The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression

BACKGROUND: Downregulation of epithelial markers and upregulation of mesenchymal markers are the characteristics of the epithelial to mesenchymal transition (EMT) program, which provides the metastatic advantage of breast cancer. However, the mechanism underlying the switch of EMT markers remains po...

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Detalles Bibliográficos
Autores principales: Zhang, Jianchao, Fan, Xiaokai, Zhou, Yunfan, Chen, Liang, Rao, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164399/
https://www.ncbi.nlm.nih.gov/pubmed/35655230
http://dx.doi.org/10.1186/s13046-022-02400-7