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The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression
BACKGROUND: Downregulation of epithelial markers and upregulation of mesenchymal markers are the characteristics of the epithelial to mesenchymal transition (EMT) program, which provides the metastatic advantage of breast cancer. However, the mechanism underlying the switch of EMT markers remains po...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164399/ https://www.ncbi.nlm.nih.gov/pubmed/35655230 http://dx.doi.org/10.1186/s13046-022-02400-7 |