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Evolutionary perspectives, heterogeneity and ovarian cancer: a complicated tale from past to present

Ovarian cancer is composed of a complex system of cells best described by features such as clonal evolution, spatial and temporal genetic heterogeneity, and development of drug resistance, thus making it the most lethal gynecologic cancer. Seminal work on cancer as an evolutionary process has a long...

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Detalles Bibliográficos
Autores principales: Achimas-Cadariu, Patriciu, Kubelac, Paul, Irimie, Alexandru, Berindan-Neagoe, Ioana, Rühli, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164402/
https://www.ncbi.nlm.nih.gov/pubmed/35659345
http://dx.doi.org/10.1186/s13048-022-01004-1