Bayesian mendelian randomization with study heterogeneity and data partitioning for large studies

BACKGROUND: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often overlooked. When dealing with large studies, recently devel...

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Detalles Bibliográficos
Autores principales: Zou, Linyi, Guo, Hui, Berzuini, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164425/
https://www.ncbi.nlm.nih.gov/pubmed/35658839
http://dx.doi.org/10.1186/s12874-022-01619-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164425/
https://www.ncbi.nlm.nih.gov/pubmed/35658839
http://dx.doi.org/10.1186/s12874-022-01619-4

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