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Bayesian mendelian randomization with study heterogeneity and data partitioning for large studies
BACKGROUND: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often overlooked. When dealing with large studies, recently devel...
Autores principales: | Zou, Linyi, Guo, Hui, Berzuini, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164425/ https://www.ncbi.nlm.nih.gov/pubmed/35658839 http://dx.doi.org/10.1186/s12874-022-01619-4 |
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