Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques

Pediatric SARS-CoV-2 vaccines are needed that elicit immunity directly in the airways, as well as systemically. Building on pediatric parainfluenza virus vaccines in clinical development, we generated a live-attenuated parainfluenza virus-vectored vaccine candidate expressing SARS-CoV-2 prefusion-st...

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Detalles Bibliográficos
Autores principales: Nouën, Cyril Le, Nelson, Christine E., Liu, Xueqiao, Park, Hong-Su, Matsuoka, Yumiko, Luongo, Cindy, Santos, Celia, Yang, Lijuan, Herbert, Richard, Castens, Ashley, Moore, Ian N., Wilder-Kofie, Temeri, Moore, Rashida, Walker, April, Zhang, Peng, Lusso, Paolo, Johnson, Reed F., Garza, Nicole L., Via, Laura E., Munir, Shirin, Barber, Daniel, Buchholz, Ursula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164439/
https://www.ncbi.nlm.nih.gov/pubmed/35665011
http://dx.doi.org/10.1101/2022.05.21.492923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164439/
https://www.ncbi.nlm.nih.gov/pubmed/35665011
http://dx.doi.org/10.1101/2022.05.21.492923

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