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FANCC deficiency mediates microglial pyroptosis and secondary neuronal apoptosis in spinal cord contusion

BACKGROUND: Traumatic spinal cord injury (SCI)-induced neuroinflammation results in secondary neurological destruction and functional disorder. Previous findings showed that microglial pyroptosis plays a crucial role in neuroinflammation. Thus, it is necessary to conduct a comprehensive investigatio...

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Detalles Bibliográficos
Autores principales: Xia, Mingjie, Li, Xinyu, Ye, Suhui, Zhang, Qinyang, Zhao, Tianyu, Li, Rulin, Zhang, Yanan, Xian, Minghan, Li, Tianqi, Li, Haijun, Hong, Xin, Zheng, Shengnai, Qian, Zhanyang, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164466/
https://www.ncbi.nlm.nih.gov/pubmed/35659106
http://dx.doi.org/10.1186/s13578-022-00816-4