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Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes

BACKGROUND: Three-quarters of bladder cancer patients present with early-stage disease (non-muscle-invasive bladder cancer, NMIBC, UICC TNM stages Ta, T1 and Tis); however, most next-generation sequencing studies to date have concentrated on later-stage disease (muscle-invasive BC, stages T2+). We u...

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Detalles Bibliográficos
Autores principales: Goel, Anshita, Ward, Douglas G., Noyvert, Boris, Yu, Minghao, Gordon, Naheema S., Abbotts, Ben, Colbourne, John K., Kissane, Stephen, James, Nicholas D., Zeegers, Maurice P., Cheng, Kar Keung, Cazier, Jean-Baptiste, Whalley, Celina M., Beggs, Andrew D., Palles, Claire, Arnold, Roland, Bryan, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164468/
https://www.ncbi.nlm.nih.gov/pubmed/35655252
http://dx.doi.org/10.1186/s13073-022-01056-4