Histone deacetylase 3 facilitates TNFα-mediated NF-κB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection

BACKGROUND: As important enzymes regulating acetylation, histone deacetylases (HDACs) participate in a series of cell physiological process. However, the mechanisms responsible for individual HDAC family members in regulating innate immunity remained to be elucidated. Here we sought to reveal the me...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Liping, Chen, Shengchuan, Xia, Jingyan, Zhou, Ying, Peng, Linan, Fan, Huimin, Han, Yu, Duan, Lihua, Cheng, Genhong, Yang, Heng, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164478/
https://www.ncbi.nlm.nih.gov/pubmed/35658939
http://dx.doi.org/10.1186/s13578-022-00814-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164478/
https://www.ncbi.nlm.nih.gov/pubmed/35658939
http://dx.doi.org/10.1186/s13578-022-00814-6

Ejemplares similares