Antidotal treatment of botulism in rats by continuous infusion with 3,4-diaminopyridine

Botulinum neurotoxins (BoNTs) are highly potent, select agent toxins that inhibit neurotransmitter release at motor nerve terminals, causing muscle paralysis and death by asphyxiation. Other than post-exposure prophylaxis with antitoxin, the only treatment option for symptomatic botulism is intubati...

Descripción completa

Detalles Bibliográficos
Autores principales: Machamer, James B., Vazquez-Cintron, Edwin J., O’Brien, Sean W., Kelly, Kyle E., Altvater, Amber C., Pagarigan, Kathleen T., Dubee, Parker B., Ondeck, Celinia A., McNutt, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164507/
https://www.ncbi.nlm.nih.gov/pubmed/35659174
http://dx.doi.org/10.1186/s10020-022-00487-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164507/
https://www.ncbi.nlm.nih.gov/pubmed/35659174
http://dx.doi.org/10.1186/s10020-022-00487-4

Ejemplares similares