Microvesicle-camouflaged biomimetic nanoparticles encapsulating a metal-organic framework for targeted rheumatoid arthritis therapy

BACKGROUND: Methotrexate (MTX) has been highlighted for Rheumatoid arthritis (RA) treatment, however, MTX does not accumulate well at inflamed sites, and long-term administration in high doses leads to severe side effects. In this study, a novel anti-RA nanoparticle complex was designed and construc...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Jia, Ming, Zheng, Xiu, Wang, Chenglong, Zhou, Yun, Pan, Hong, Liu, Yan, Lu, Ji, Mei, Zhiqiang, Li, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164508/
https://www.ncbi.nlm.nih.gov/pubmed/35658866
http://dx.doi.org/10.1186/s12951-022-01447-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164508/
https://www.ncbi.nlm.nih.gov/pubmed/35658866
http://dx.doi.org/10.1186/s12951-022-01447-0

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