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Microvesicle-camouflaged biomimetic nanoparticles encapsulating a metal-organic framework for targeted rheumatoid arthritis therapy
BACKGROUND: Methotrexate (MTX) has been highlighted for Rheumatoid arthritis (RA) treatment, however, MTX does not accumulate well at inflamed sites, and long-term administration in high doses leads to severe side effects. In this study, a novel anti-RA nanoparticle complex was designed and construc...
Autores principales: | Wang, Yao, Jia, Ming, Zheng, Xiu, Wang, Chenglong, Zhou, Yun, Pan, Hong, Liu, Yan, Lu, Ji, Mei, Zhiqiang, Li, Chunhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164508/ https://www.ncbi.nlm.nih.gov/pubmed/35658866 http://dx.doi.org/10.1186/s12951-022-01447-0 |
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