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Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier

BACKGROUND: Mammalian Claudin-5 is the main endothelial tight junction component maintaining blood-brain barrier (BBB) permeability, while Claudin-1 and -3 seal the paracellular space of choroid plexus (CP) epithelial cells contributing to the blood-cerebrospinal fluid barrier (BCSFB). In zebrafish,...

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Detalles Bibliográficos
Autores principales: Li, Yanyu, Wang, Chunchun, Zhang, Liang, Chen, Bing, Mo, Yuqian, Zhang, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164509/
https://www.ncbi.nlm.nih.gov/pubmed/35658877
http://dx.doi.org/10.1186/s12987-022-00337-9