Nicotinamide drives T cell activation in the mammary tumor microenvironment

Nicotinamide (NAM, a variant of vitamin B(3)) has recently been shown to accelerate the activation of human CD4(+) and CD8(+) T cells exposed to repeated CD3/CD28 agonism in vitro. Here, we demonstrate that T cells infiltrating mouse mammary carcinomas that are therapeutically controlled by NAM also...

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Detalles Bibliográficos
Autores principales: Hu, Yang, Bloy, Norma, Elemento, Olivier, Buqué, Aitziber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164530/
https://www.ncbi.nlm.nih.gov/pubmed/35659314
http://dx.doi.org/10.1186/s12967-022-03454-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164530/
https://www.ncbi.nlm.nih.gov/pubmed/35659314
http://dx.doi.org/10.1186/s12967-022-03454-z

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