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MEDB-63. Deciphering the role of LIN28B in Group 3 medulloblastoma

BACKGROUND: Children with Group 3 medulloblastoma (MB) have a very poor long-term outcome and many do not survive beyond 5 years. Several drivers for Group 3 MB have been identified but none have resulted in targeted therapy to date. LIN28B is a stem cell factor that is upregulated in Group 3 medull...

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Detalles Bibliográficos
Autores principales: Shahab, Shubin, Sun, Jessica, Schnepp, Robert, MacDonald, Tobey, Kenney, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164639/
http://dx.doi.org/10.1093/neuonc/noac079.437