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ETMR-11. Transcriptional changes upon knockdown of alteredBCOR/BCORL1 transcripts in preclinical models of CNS embryonal tumors with BCOR-related alterations

BCL-6 transcriptional corepressor (BCOR) is an epigenetic regulator that silences gene expression mainly via the polycomb repressive complex 1.1 (PRC1.1). BCOR genomic alterations are found in a variety of different tumors and recently central nervous system (CNS) tumors with BCOR internal tandem du...

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Detalles Bibliográficos
Autores principales: Piontek, Martin, Kirchhofer, Dominik, Gabler, Lisa, Lötsch-Gojo, Daniela, Pirker, Christine, Schmitt-Hoffner, Felix, Jaunecker, Carola N, Kool, Marcel, Berger, Walter, Gojo, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164644/
http://dx.doi.org/10.1093/neuonc/noac079.189