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MEDB-61. Genetic alterations ofTP53 andOTX2 indicate increased risk of relapse in WNT medulloblastomas

PURPOSE: This genetic analysis of WNT-activated medulloblastomas (WNT-MBs) aimed to re-evaluate the prognostic impact of TP53 mutations and to identify specific chromosomal aberrations as possible prognostic markers in a retrospective cohort of patients treated according to the protocols of the HIT...

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Detalles Bibliográficos
Autores principales: Goschzik, Tobias, Mynarek, Martin, Dörner, Evelyn, Aretz, Stefan, Rutkowski, Stefan, Pietsch, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164707/
http://dx.doi.org/10.1093/neuonc/noac079.435