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MEDB-90. Iron Imbalance Can Potentiate Cisplatin Response in Pediatric Medulloblastoma by Regulating Ferroptosis

Medulloblastoma (MB), the most common malignant pediatric brain tumor, is a leading cause of childhood mortality. Of the four primary subgroups, patients with group 3 tumors have the poorest prognosis. Loss of chromosome 17p is a high-risk feature associated with poor outcomes in group 3 tumors. We...

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Detalles Bibliográficos
Autores principales: Kanchan, Ranjana, Perumal, Naveenkumar, Khan, Parvez, Doss, David, Venkata, Ramakanth Chirravuri, Thapa, Ishwor, Vengoji, Raghupathy, Kaushal, Jyoti, Siddiqui, Jawed, Nasser, Mohd Wasim, Batra, Surinder, Mahapatra, Sidhartha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164725/
http://dx.doi.org/10.1093/neuonc/noac079.464