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OTHR-41. Amplification of the PLAG family genes – PLAGL1 and PLAGL2 – is a key feature of a novel embryonal CNS tumor type

Pediatric central nervous system (CNS) tumors differ substantially from their adult counterparts, are marked by considerable molecular and clinical heterogeneity, and diagnosis through histopathology alone can be challenging. Using DNA methylation-based CNS tumor classification in combination with c...

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Detalles Bibliográficos
Autores principales: Keck, Michaela-Kristina, Sill, Martin, Wittmann, Andrea, Kumar, Piyush Joshi, Stichel, Damian, Sievers, Philipp, Wefers, Annika K, Roncaroli, Federico, Hayden, James, McCabe, Martin G, Kranendonk, Mariëtte E G, Zapotocky, Michal, Vasiljevic, Alexandre, Schüller, Ulrich, Sturm, Dominik, Blattner-Johnson, Mirjam, von Deimling, Andreas, Korshunov, Andrey, Sahm, Felix, Perry, Arie, Solomon, David, Pfister, Stefan, Jones, David T W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164753/
http://dx.doi.org/10.1093/neuonc/noac079.579