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OTHR-41. Amplification of the PLAG family genes – PLAGL1 and PLAGL2 – is a key feature of a novel embryonal CNS tumor type
Pediatric central nervous system (CNS) tumors differ substantially from their adult counterparts, are marked by considerable molecular and clinical heterogeneity, and diagnosis through histopathology alone can be challenging. Using DNA methylation-based CNS tumor classification in combination with c...
Autores principales: | Keck, Michaela-Kristina, Sill, Martin, Wittmann, Andrea, Kumar, Piyush Joshi, Stichel, Damian, Sievers, Philipp, Wefers, Annika K, Roncaroli, Federico, Hayden, James, McCabe, Martin G, Kranendonk, Mariëtte E G, Zapotocky, Michal, Vasiljevic, Alexandre, Schüller, Ulrich, Sturm, Dominik, Blattner-Johnson, Mirjam, von Deimling, Andreas, Korshunov, Andrey, Sahm, Felix, Perry, Arie, Solomon, David, Pfister, Stefan, Jones, David T W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164753/ http://dx.doi.org/10.1093/neuonc/noac079.579 |
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